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[ATTD2011]糖尿病治疗新技术以及处理儿童糖尿病的相关问题
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——第四届糖尿病领先技术与治疗国际研讨会(ATTD 2011)主席Moshe Phillip博士现场采访
专家访谈 综合领域 作者:Phillip 来源:国际糖尿病 2011/3/4 16:44:00    加入收藏
内容概要:

   《国际糖尿病》:毫无疑问,人工胰腺是本届大会非常热门的话题。至于人工胰腺何时能够投入使用,专家有多种不同的看法。您觉得人工胰腺何时会正式投入使用?
    Phillip博士:可以明确的是,即使是在目前,我们也可以应用未来的人工胰腺的一些特点。我们已经能够半自动地输注胰岛素。我们还能持续监测血糖。我们能够根据公式就注射多少胰岛素向患者提出建议。我们还有一些新技术,尽管还没有上市(因为还没有得到美国食品药品监督管理局的批准),但是这些技术在欧洲已经投入临床使用,例如当患者发生低血糖时停止给予胰岛素。因此,我们已经迈出了闭环式胰岛素泵的最初几步。毫无疑问在几年内,可能是三、五年,我们一定会研发出夜间闭环式胰岛素泵。对于很多患者来讲,夜间应用闭环式胰岛素泵将是一个巨大的变化。夜间是一天当中最危险的时段,此时患者没办法控制自己的血糖变化。患者在睡觉,患者的父母也在睡觉,没办法控制血糖,因此我们相信我们能够提前计划,知道血糖在夜间的变化情况。目前,我们已经能够实现夜间的闭环控制,在本次大会期间有几个不同的研究小组做了这方面的工作,他们将公布有关夜间控制血糖的数据。我想,这一技术将在几年内投入临床使用。

    <International Diabetes>:Artificial pancreas is of course a very hot topic. There are as many different opinions as there are experts on that subject as to when the artificial pancreas may be ready for use. What is your opinion on when the artificial pancreas might be ready for public use?
    Dr Phillip: It is clear, even now, that we are able to use some of the features that the artificial pancreas eventually will have. We already are able to infuse insulin semi-automatically. We are now able to measure blood glucose levels constantly. We are already able to give a patient advice on how much insulin to inject based on algorithms. And we already have access to new technologies, which although are not yet in the marketplace (as they have not been approved by the American FDA), but are in clinical use in Europe, for example, to suspend insulin delivery in patients where hypoglycemia occurs. So we are already seeing the first steps to closing the loop and I have no doubt in a few years, I don’t know whether it might be three or five, we will definitely have the ability to close the loop at night first. Closing the loop at night will be a major change for many of our patients. Night time is the most dangerous part of the day when patients have no control over what happens to their glucose levels. They are asleep and parents of children are asleep and there is no way to control the blood glucose level so we trust the assumption that we can plan in advance how the blood glucose level will behave during the night. The ability to close the loop during the night already exists and we have seen several attempts by different groups during the meeting who have presented data showing how they have been able to control blood glucose levels during the night. I think this will be clinically available within a few years.



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网站用户: 王仁友 时间:2011/3/13 16:59:45
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